Publications

† joint first author. * corresponding author.

2026

1. 2026
   Amino acid reprogramming and biofilm-specific tricarboxylate transporters in PET-degrading Piscinibacter sakaiensis

   Lim Hao Wei, Xu Jiabao†*, Koh Jonas, Cao Bin, Tu Weiming · Applied and Environmental Microbiology
   DOI
2. 2026
   Raman spectroscopy reveals a novel mechanism by which Cyclin Y promotes breast cancer progression by regulating lipid metabolism

   Zhang Lingxian, Kong Deyu, Chen Gang, Mei Jiayu, Luo Yaogan, Xu Jiabao*, and 3 more · Acta Biochimica et Biophysica Sinica
   DOI
3. 2026
   Promoter selection reduces phenotypic heterogeneity and improves bioproduction

   Patel Davina, Shabestary Kiyan, Xu Jiabao, Klemm Cinzia, Huang Wei E., Ledesma-Amaro Rodrigo · Trends in Biotechnology
   DOI
4. 2026
   Editorial: Advances in combating antimicrobial resistance: focus on diagnosis, therapy, and prevention

   Yu Yuetian, Xu Jiabao, Lin Bin, Priputnevich Tatiana V., Munir Muhammad Usman, Nang Sue C. Chin, and 1 more · Frontiers in Cellular and Infection Microbiology
   DOI
5. 2026
   Machine learning-driven optimization of metabolic balance for β-carotene production

   Tu Weiming, Xu Jiabao*, Ma Yongshuo, Katsimpouras Constantinos, Stephanopoulos Gregory · Metabolic Engineering
   DOI
6. 2026
   Rapid culture-free diagnosis of clinical pathogens via integrated microfluidic-Raman micro-spectroscopy

   Li Yuetao, Xu Jiabao†, Yi Xiaofei, Li Xiaobo, Luo Yanjun, Glidle Andrew, and 16 more · Nature Communications
   DOI

2025

1. 2025
   Microwell-assembled aluminum substrates for enhanced single-cell analysis: A novel approach for cancer cell profiling by Raman spectroscopy

   Wang Yuntong, Qu Yue, Wang Huan, Xue Ying, Liang Peng, Xu Jiabao*, and 6 more · Talanta
   DOI
2. 2025
   Using Single-Cell Raman Microspectroscopy to Profile Human Peripheral Blood Mononuclear Cells

   Gan Elizabeth, Stoker Megan, Guo Edie, Morten Karl J., Xu Jiabao · Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Methods and Protocols (Springer US)
   DOI
3. 2025
   Age-Dependent Metabolic Signatures in Mouse Oocytes Revealed by Single-Cell Raman Spectroscopy and High-Resolution Imaging

   Xiong Wei, Sun Aijun, Gui Ting, Xiao Yaling, Wang Xue, Xu Jiabao*, and 4 more · iMetaMed
   DOI
4. 2025
   The microbiome in cancer

   Lin Anqi, Xiong Minying, Jiang Aimin, Huang Lihaoyun, Wong Hank Z. H., Xu Jiabao, and 45 more · iMeta
   DOI
5. 2025
   Single-Cell Analysis Reveals the Impact of tumor-derived matrix on Cancer-Associated Fibroblasts

   Peng Qiyun, Sun Haojie, Neilson Lisa J, Maknitikul Sitang, Xu Jiabao, Kong Lingjiang, and 2 more · Proceedings of the 2024 9th International Conference on Biomedical Imaging, Signal Processing
   DOI

2024

1. 2024
   High-throughput single-cell sorting by stimulated Raman-activated cell ejection

   Zhang Jing, Lin Haonan, Xu Jiabao*, Zhang Meng, Ge Xiaowei, Zhang Chi, and 2 more · Science Advances
   DOI
2. 2024
   Synthesis and characterization of amine-functionalized graphene as a nitric oxide-generating coating for vascular stents

   Tabish Tanveer A., Hussain Mian Zahid, Zhu Yangzhi, Xu Jiabao, Huang Wei E., Diotallevi Marina, and 5 more · Applied Physics Reviews
   DOI
3. 2024
   Rapid profiling of fish cell nitrogen metabolism with single-cell Raman spectroscopy: Unveiling enzyme's role in ammonia detoxification

   Peng Qiyun, Dong Yingfu, Chen Yecang, Glidle Andrew, Kong Lingjiang, Xu Jiabao*, and 2 more · Talanta
   DOI
4. 2024
   S-nitrosocysteamine-functionalised porous graphene oxide nanosheets as nitric oxide delivery vehicles for cardiovascular applications

   Tabish Tanveer A., Hussain Mian Zahid, Zervou Sevasti, Myers William K., Tu Weiming, Xu Jiabao, and 6 more · Redox Biology
   DOI
5. 2024
   Raman micro-spectroscopy as a tool to study immunometabolism

   Xu Jiabao*, Morten Karl J · Biochemical Society Transactions
   DOI
6. 2024
   A metabolic map and artificial intelligence-aided identification of nasopharyngeal carcinoma via a single-cell Raman platform

   Xu Jiabao†, Chen Dayang, Wu Wei, Ji Xiang, Dou Xiaowen, Gao Xiaojuan, and 4 more · British Journal of Cancer
   DOI

2023

1. 2023
   Engineering artificial photosynthesis based on rhodopsin for CO2 fixation

   Tu Weiming, Xu Jiabao, Thompson Ian P., Huang Wei E. · Nature Communications
   DOI
2. 2023
   Artificial intelligence-aided rapid and accurate identification of clinical fungal infections by single-cell Raman spectroscopy

   Xu Jiabao, Luo Yanjun, Wang Jingkai, Tu Weiming, Yi Xiaofei, Xu Xiaogang, and 7 more · Frontiers in Microbiology
   DOI
3. 2023
   Editorial: Single-cell tools to combat antimicrobial resistance

   Xu Jiabao*, Cui Li, Song Yizhi · Frontiers in Microbiology
   DOI
4. 2023
   Metabolic Reprogramming in Colon Cancer Cells Persistently Infected with Newcastle Disease Virus

   Yu Tong, Jadhav Archana Chandrabhan, Xu Jiabao*, Harris Adrian L., Nair Venugopal, Huang Wei E. · Cancers
   DOI
5. 2023
   Developing a Blood Cell-Based Diagnostic Test for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Using Peripheral Blood Mononuclear Cells

   Xu Jiabao, Lodge Tiffany, Kingdon Caroline, Strong James W. L., Maclennan John, Lacerda Eliana, and 4 more · Advanced Science
   DOI

2022

1. 2022
   Engineering a Rhodopsin-Based Photo-Electrosynthetic System in Bacteria for CO2 Fixation

   Davison Paul A., Tu Weiming, Xu Jiabao, Della Valle Simona, Thompson Ian P., Hunter C. Neil, and 1 more · ACS Synthetic Biology
   DOI
2. 2022
   High-Speed Diagnosis of Bacterial Pathogens at the Single Cell Level by Raman Microspectroscopy with Machine Learning Filters and Denoising Autoencoders

   Xu Jiabao, Yi Xiaofei, Jin Guilan, Peng Di, Fan Gaoya, Xu Xiaogang, and 4 more · ACS Chemical Biology
   DOI
3. 2022
   Raman-integrated optical photothermal infrared microscopy: technology and applications

   Li Xiaojie, Xu Jiabao, Cheng Ji-Xin · Molecular and Laser Spectroscopy: Advances and Applications, Volume 3
   DOI
4. 2022
   Diagnosis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome With Partial Least Squares Discriminant Analysis: Relevance of Blood Extracellular Vesicles

   González-Cebrián Alba, Almenar-Pérez Eloy, Xu Jiabao, Yu Tong, Huang Wei E., Giménez-Orenga Karen, and 6 more · Frontiers in Medicine
   DOI

2021

1. 2021
   Unveiling Cancer Metabolism through Spontaneous and Coherent Raman Spectroscopy and Stable Isotope Probing

   Xu Jiabao*, Yu Tong, Zois Christos E., Cheng Ji-Xin, Tang Yuguo, Harris Adrian L., and 1 more · Cancers
   DOI
2. 2021
   Regulation and characterization of mutants of fixABCX in Rhizobium leguminosarum

   Webb Isabel, Xu Jiabao, Sanchez-Cañizares Carmen, Karunakaran Ramakrishnan, Ramachandran Vinoy, Rutten Paul, and 4 more · Molecular Plant-Microbe Interactions
   DOI
3. 2021
   Classification and Identification of Archaea Using Single-Cell Raman Ejection and Artificial Intelligence: Implications for Investigating Uncultivated Microorganisms

   Wang Yi, Xu Jiabao, Cui Dongyu, Kong Lingchao, Chen Songze, Xie Wei, and 1 more · Analytical Chemistry
   DOI

2020

1. 2020
   Fingerprinting Bacterial Metabolic Response to Erythromycin by Raman-Integrated Mid-Infrared Photothermal Microscopy

   Xu Jiabao, Li Xiaojie, Guo Zhongyue, Huang Wei E., Cheng Ji-Xin · Analytical Chemistry
   DOI
2. 2020
   A single-cell Raman-based platform to identify developmental stages of human pluripotent stem cell-derived neurons

   Hsu Chia-Chen, Xu Jiabao†, Brinkhof Bas, Wang Hui, Cui Zhanfeng, Huang Wei E., and 1 more · Proceedings of the National Academy of Sciences
   DOI
3. 2020
   Elevated intracellular cyclic-di-GMP level in Shewanella oneidensis increases expression of c-type cytochromes

   Ng Chun Kiat, Xu Jiabao, Cai Zhao, Yang Liang, Thompson Ian P., Huang Wei E., and 1 more · Microbial Biotechnology
   DOI
4. 2020
   Raman‐activated sorting of antibiotic‐resistant bacteria in human gut microbiota

   Wang Yi, Xu Jiabao, Kong Lingchao, Li Bei, Li Hang, Huang Wei E., and 1 more · Environmental Microbiology
   DOI

2019

1. 2019
   Raman–deuterium isotope probing to study metabolic activities of single bacterial cells in human intestinal microbiota

   Wang Yi, Xu Jiabao, Kong Lingchao, Liu Tang, Yi Lingbo, Wang Hongjuan, and 2 more · Microbial Biotechnology
   DOI
2. 2019
   Raman profiling of embryo culture medium to identify aneuploid and euploid embryos

   Liang Bo, Gao Yuan, Xu Jiabao, Song Yizhi, Xuan Liming, Shi Ting, and 5 more · Fertility and Sterility
   DOI
3. 2019
   Effective removal of methyl siloxane from water by sewage activated sludge microbes: biodegradation behavior and characteristics of microbial community

   Wang Yi, Zhang Zi-Feng, Xu Xi-Jun, Chen Chuan, Xu Jia-Bao, Kong Ling-Chao, and 4 more · Bioresource Technology Reports
   DOI
4. 2019
   Single-Cell and Time-Resolved Profiling of Intracellular Salmonella Metabolism in Primary Human Cells

   Xu Jiabao, Preciado-Llanes Lorena, Aulicino Anna, Decker Christoph Martin, Depke Maren, Gesell Salazar Manuela, and 3 more · Analytical Chemistry
   DOI
5. 2019
   Development of Aspirin-Inducible Biosensors in Escherichia coli and SimCells

   Chen Jack Xiaoyu, Steel Harrison, Wu Yin-Hu, Wang Yun, Xu Jiabao, Rampley Cordelia P. N., and 3 more · Applied and Environmental Microbiology
   DOI

2018

1. 2018
   A new approach to find biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) by single-cell Raman micro-spectroscopy

   Xu Jiabao, Potter Michelle, Tomas Cara, Elson Joanna L., Morten Karl J., Poulton Joanna, and 4 more · Analyst
   DOI
2. 2018
   Effect of Laser Irradiation on Cell Function and Its Implications in Raman Spectroscopy

   Yuan Xiaofei, Song Yanqing, Song Yizhi, Xu Jiabao, Wu Yinhu, Glidle Andrew, and 5 more · Applied and Environmental Microbiology
   DOI

2017

1. 2017
   Raman-Deuterium Isotope Probing for in-situ identification of antimicrobial resistant bacteria in Thames River

   Song Yizhi, Cui Li, López José Ángel Siles, Xu Jiabao, Zhu Yong-Guan, Thompson Ian P., and 1 more · Scientific Reports
   DOI
2. 2017
   Label-Free Discrimination of Rhizobial Bacteroids and Mutants by Single-Cell Raman Microspectroscopy

   Xu Jiabao, Webb Isabel, Poole Philip, Huang Wei E. · Analytical Chemistry
   DOI
3. 2017
   Raman Deuterium Isotope Probing Reveals Microbial Metabolism at the Single-Cell Level

   Xu Jiabao, Zhu Di, Ibrahim Aliyu D., Allen Christopher C. R., Gibson Christopher M., Fowler Patrick W., and 2 more · Analytical Chemistry
   DOI